We have highlighted some clinical trials currently recruiting patients. Each has a specific purpose related to aplastic anemia, MDS, or PNH. Should you consider a clinical trial? Ask your doctor or contact the study coordinators for further information. Learn more in the Clinical Trials section.
If you only want to see studies that are currently recruiting patients, select that option from the “recruitment” line at the beginning of the advanced search. To locate a clinical trial in your state, use the “advanced search” feature. Under locations, select your state(s) and your country.
Search for aplastic anemia studies actively recruiting patients. The following are a sample of the 79 open studies recruiting aplastic anemia patients in the United States.
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Title/Link to more information |
Study Purpose |
Study Coordinator |
| Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases | This is a Phase II trial to determine the ability of a reduced intensity conditioning regimen to allow successful engraftment with CD3+ /CD19+ depleted peripheral stem cell grafts from mismatched donors. There are two conditioning regimens depending upon patient diagnosis and age. |
This study is being conducted at the Children’s Hospital of Philadelphia, PA Contact: Margaret Tartaglione, RN, 215-590-4029 or tartaglione@email.chop.edu Please refer to this study by its ClinicalTrials.gov identifier: NCT02277639 |
| Genetic Variation and Variability in Posaconazole Pharmacokinetics in Children | The main goal of this study is to see how the body breaks down an antifungal drug named posaconazole in children with certain cancers, blood disorders, or transplantation of bone marrow or similar blood cells. This study will also help us learn whether a child's age, genetics, or disease affect how well the body breaks down posaconazole. | This study is being conducted at Children’s Mercy Hospital in Kansas City, Missouri. Contact: Joanne L Thurber, RN, CCRC 816-234-3076 jthurber@cmh.edu Please refer to this study by its ClinicalTrials.gov identifier: NCT02358499 |
Seach for myelodysplastic syndromes studies actively recruiting patients. The following MDS studies are a sample of the 315 studies recruiting MDS patients in the United States.
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Title/Link to more information |
Study Purpose |
Study Coordinator |
| The Myelodysplasia Transplantation-Associated Outcomes (MDS-TAO) Study |
The purpose of this observational study is to compare overall survival in older adults with myelodysplastic syndromes (MDS) who receive reduced intensity conditioning hematopoietic stem cell transplant (RIC HSCT) versus those who do not receive HSCT. | This study is being conducted in Boston, MA. Beth Israel Deaconess Medical Center—contact David Avigan, MD 616-667-9920 davigan@bidmc.harvard.edu Dana Farber Cancer Institute—contact Gregory Abel, MD, MPH 717-632-2304 GAABEL@PARTNERS.ORG Massachusetts General Hospital—contact Yi-Ben Chen, MD 617-726-1124 yachen@partners.org Please refer to this study by its ClinicalTrials.gov identifier: NCT02390414 |
| The goal of this research study is to test a quality-of-life questionnaire called QUALMS-1 in patients with MDS. | This study is being conducted in Florida, Maryland, Massachusetts, New York, Ohio, and Texas Contact: Guillermo Garcia-Manero, MD 713-745-3428 Please refer to this study by its ClinicalTrials.gov identifier: NCT02378701 |
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| GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 10/10 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant |
This is a pilot study which will be done in a small number of patients. The purpose of this study is to test the safety and benefit of giving a type of chemotherapy - cyclophosphamide - after the transplant to prevent graft versus host disease (GVHD) in patients with abnormal kidney function. GVHD is one of the most common complications of a stem cell transplant. |
This study is being conducted in NY. |
Please search for a list of current paroxysmal nocturnal hemoglobinuria studies actively recruiting patients. The following are a recent sample of the 9 studies recruiting PNH patients in the United States.
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Title/Link to more information |
Study Purpose |
Study Coordinator |
| A Phase I Study to Assess the Safety APL-2 as an Add-On to Standard of Care in Subjects With PNH | This study will be the initial exploration of APL-2 in patients with PNH. The assessments of the safety, tolerability, PK, and PD following administration of single and multiples doses of APL-2 will guide decisions to further develop the drug. | This study is being conducted at the University of Louisville, KY Contact: Candace Depp pnh@apellis.com Please refer to this study by its ClinicalTrials.gov identifier: NCT02264639 |